ABOUT TBRI

What does Tampa Bay Research Institute do and how is it different from other research institutes or charities?

TBRI is dedicated to the study, cure and prevention of cancer and chronic infectious diseases. We are similar to a number of other research institutes in the U.S. and abroad in that we are interdisciplinary in nature and focused on biomedical research. However, we are somewhat different in that we are dedicated to exploring unique biological pathways of the human immune system as they relate to several diseases, rather than maintaining a focus on a single disease. In addition, TBRI provides valuable community health education that is backed by the latest biomedical research.

Are you affiliated with any universities or hospitals in the local area or internationally?

TBRI is not formally affiliated with any university or hospital; however, we are available to and actively collaborate with universities and hospitals throughout the world as a scientific resource.

We are an independent biomedical research institute. Our independence allows us to be a neutral, science-based entity. We believe this flexibility enables us to rapidly focus our resources on promising areas of scientific study rather than on other, non-scientific requirements sometimes imposed by certain funding sources. Best of all, we are available to serve all institutions and colleges that require our assistance or cooperation, upon request.

Are there universities or institutions in which TBRI has participated in joint studies?

Over the last 30 years, TBRI has conducted scientific collaborations with a number of prestigious institutions, including All Children’s Hospital, Eckerd College, Emory University in Atlanta, the Howard Hughes Medical Institute at UCLA, Johns Hopkins University in Baltimore, the Kitasato Institute in Japan, the Moffitt Cancer Center at the University of South Florida (USF), North Carolina State University in Raleigh, St. Pete College (SPC), Suncoast Hospital in Largo, Tampa General Hospital, the University of Chicago, and the University of Montreal in Canada.

To date, TBRI has trained over 100 undergraduate and graduate students from the U.S. and abroad, as well as a number of postdoctoral fellows.

What research projects does the Institute currently have under way?

Investigating novel ways to develop vaccines against cancer and viral infections

Investigating the immune modulating activity of PPC (a proprietary and patented extract prepared from pine cones)

How is TBRI funded?

TBRI obtains its funds through private foundation and government grants, contributions, income from special events, and a membership program.

What is the ratio of income from federal grants, local grants, private and corporate donations, special events, etc.?

This has evolved over the years from almost all government grants during the first 15 years, to all private contributions and foundation grants during the following 15 years, to a combination of funding sources in the past year and a half. Details are published in our Annual Report.

How much is spent on research, development and administration?

We are proud that only about 10% of our funding is earmarked for development. The balance is devoted to research and administration. According to the Good Practices Standards as recognized by the Association of Fund Raising Professionals (AFP), development costs may typically run as high as 25% for a non-profit organization. TBRI has maintained this figure at 5-10% over the past fifteen years.

What areas of research does TBRI plan to address, based upon results obtained from your outstanding or pending grants?

At any given time, TBRI has numerous grants on the drawing board that address various chronic and infectious diseases, as well as health education program grants. We hope to continue to expand our efforts in all of these areas. Since TBRI is a non-profit organization, we must control our costs and carefully plan our growth; therefore, grants and community contributions are very important components in ensuring the continuity of our work.

Pine Cone extract: What is it?

The extract was developed through TBRI’s research efforts. Technically, it is termed PPC (a polyphenylpropenoid-polysaccharide complex). It was initially sold as a dietary supplement to the general public by a third party. However, due to TBRI’s promising research results it may be developed as an ethical drug—for example, as an “adjuvant” for use in conjunction with vaccine administration. This question is being carefully evaluated by our scientific staff and our Scientific Advisory Committee. In addition, our corporate and patent attorneys, as well as the Food and Drug Administration (FDA) and the National Institutes of Health (NIH), are working closely with us on this matter.

Where do the pine cones come from?

The pine cones come from selected U.S. pine tree species—in a manner similar to that of aspirin, which historically was derived from the bark of the willow tree.

Is there a medical doctor who has witnessed the benefits of the Pine Cone extract and is willing to vouch for its healing properties?

There are a number of medical doctors who are actively investigating the benefits of the Pine Cone extract, in collaboration with TBRI’s research scientists.

Do you have an inventory list of all laboratory equipment on the premises?

Yes. The certified public accountants (CPAs) who conduct our annual audits require that we maintain a detailed itemized listing of all major scientific and administrative equipment.